Cardiology

Posted September 16, 2026

The Deb Laboratory in the Division of Cardiology, Department of Medicine, at the David Geffen School of Medicine at UCLA is seeking an Assistant Project Scientist to lead research on the role of the methionine salvage pathway (MSP) and its metabolite in cardiovascular disease. This is an independent, research-intensive position within a well-funded, highly collaborative program supported by NIH grants. The successful candidate will investigate how MSP-dependent molecular and metabolic mechanisms regulate cardiac function, remodeling and organ repair, and will help translate these findings into therapeutic strategies. A Ph.D. or equivalent is required.

Key Responsibilities:

• Design, lead and execute research projects on the molecular mechanisms by which the methionine salvage pathway regulates cardiac metabolism and the cardiac epigenome in cardiovascular disease.
• Utilize and further develop genetically engineered mouse models of cardiovascular disease, including cell-type-specific conditional knockout models.
• Perform and interpret in vivo/in vitro isotope metabolic tracing, targeted and untargeted metabolomics, and energetics studies.
• Generate and analyze single-cell multi-omics sequencing, methylation sequencing and metabolomics datasets, integrating them with human heart failure cohort data.
• Establish and apply human iPSC-derived cardiomyocyte and organoid systems for mechanistic and target-validation studies.
• Prepare manuscripts, figures and conference presentations; contribute to grant applications and progress reports.
• Train and mentor graduate students, postdoctoral fellows and technicians.
• Contribute to collaborative projects on tissue repair and translational therapeutics.

Preferred Qualifications:

• Direct research experience with the cardiac metabolism research.
• Experience with mouse models and echocardiographic/hemodynamic phenotyping.
• Proficiency in standard molecular and biochemical techniques.
• Expertise in single-cell/single-nucleus multiome analysis and epigenomic profiling.
• Experience with stem cell, iPSC or organoid culture systems.
• Publications in high-impact journals in cardiovascular research, metabolism or cell biology.

The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at Cultural North Star.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

To apply, please click here – JPF11378

Posted September 16, 2026

The Shivkumar laboratory in the Division of Cardiology, Department of Medicine, at the David Geffen School of Medicine at UCLA is seeking an Assistant Project Scientist to participate in cardiac anatomy structure function studies examining the role of the autonomic nervous system in the initiation and progression of cardiac disease and arrhythmias, and its diagnostic and therapeutic relevance, as well as creating a 3D archive of datasets of cardiac anatomy for our Amara-Yad Project.

An MD, PhD, and/or equivalent degree is required.

The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at Cultural North Star.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

To apply, please click here – JPF11380

Posted September 16, 2026

The Deb Laboratory in the Division of Cardiology, Department of Medicine, at the David Geffen School of Medicine at UCLA is seeking an Assistant or Associate Project Scientist to lead our protein biochemistry and biologics production efforts. This is a staff scientist position — no independent grant-writing expectations — with a clear and critical mission: build and operate a robust in-house capability for recombinant protein expression, purification, and characterization to accelerate our biologics pipeline from bench to clinic.

This person will own the end-to-end production pipeline for recombinant proteins and antibody-based therapeutics, work closely with the PI and senior lab members to support active drug development programs, and play a central role in the lab's translational work going forward.

Key Responsibilities:

1. Design, optimize, and execute mammalian recombinant protein expression using HEK293, CHO, or equivalent systems
2. Purify proteins to high purity using affinity chromatography, size exclusion chromatography (SEC), and ion exchange chromatography on FPLC/ÄKTA platforms
3. Perform rigorous quality characterization including SDS-PAGE, western blot, ELISA, dynamic light scattering, and binding validation by SPR or BLI
4. Maintain detailed, meticulous records of all production runs, yields, and QC results
5. Collaborate with postdoctoral scientists and project scientists on protein-dependent experimental aims
6. Contribute to the preparation of research publications and grant applications as relevant
7. Evaluate and implement new expression and purification technologies as the pipeline evolves

Required Qualifications:

1. A Ph.D. or equivalent in biochemistry, protein biochemistry, molecular biology, or a closely related field is required.
2. A minimum of 5 years of hands-on experience with mammalian recombinant protein expression and purification — bacterial expression experience alone is not sufficient.

Preferred Qualifications:

1. Industry experience in a biologics, biotech, or pharmaceutical setting.
2. Experience with antibody production, engineering, or optimization.
3. Familiarity with GMP-adjacent processes and regulatory documentation.
4. Experience with binding kinetics platforms (Biacore/SPR, BLI/Octet).
5. Background in cardiovascular biology, immunology, or metabolic disease.
6. A demonstrated ability to troubleshoot complex expression and purification challenges independently.
7. An expert-level proficiency with FPLC/ÄKTA chromatography systems.
8. A strong working knowledge of protein QC methods (SDS-PAGE, SEC-HPLC, ELISA, DLS).
9. Meticulous attention to documentation and reproducibility.
10. Strong written and oral communication skills.

The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at Cultural North Star.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

To apply, please click here – JPF11382

Posted October 5, 2026

The Vaseghi laboratory in the Division of Cardiology, Department of Medicine, at the David Geffen School of Medicine at UCLA is seeking an Assistant Project Scientist with expertise in the area of cardiovascular disease to lead translational projects involving evaluation of the role of the autonomic nervous system in the development of arrhythmias and progression of heart failure and assessment of neuromodulatory therapies. In addition to driving and leading translational research projects, applicants are expected to contribute to high impact publications and grant proposals and mentor junior researchers.

Previous experience working with cardiovascular disease models in addition to the following is highly desirable:

• Expertise in independently performing animal survival and non-survival surgeries, including creation of myocardial infarcts in rodents and/or large animal models
• Expertise in cardiac physiology and electrophysiology recordings and interpretation, including vascular flow assessments
• Strong expertise in molecular biology techniques including but limited to immunohistochemistry, qPCR., ELISA
• Optogenetic techniques
• Ex-vivo and/or in-vivo neural activity recordings, analysis, and interpretation

Expectations:
Under Dr. Vaseghi’s mentorship, the Assistant Project Scientist’s research will focus on identifying specific neural and molecular pathways that occur with cardiovascular disease and drive progression of heart failure and arrhythmias. The Assistant Project Scientist will be responsible for supervising and/or performing experiments, analyzing data, and building reproducible workflows for projects. Duties will also include manuscript preparation, mentoring junior lab members, participating in academic activities such as lab meetings, seminars, grant development, and presentations at national and international meetings relevant to the areas of study in the lab.

Qualifications:
The ideal candidate should have an M.D. and/or Ph.D., or equivalent, in Physiology, Pharmacology, Neuroscience, Biology or related fields along with demonstrated expertise (4+ years of relevant post-doctoral experience) in translational studies and a strong track record of publication in peer-reviewed journals.

The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at Cultural North Star.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

To apply, please click here – JPF11350.  

Posted July 21, 2026

The Division of Cardiology in the Department of Medicine at the David Geffen School of Medicine at UCLA is seeking applications for Clinician-Educator positions in the Health Sciences Clinical Professor series at the Instructor, Assistant, Associate, or full Professor ranks. Candidates with non-invasive training and interventional training are being recruited. These positions involve participating in university-based cardiology practices throughout Santa Barbara and Montecito. Candidates are expected to be board-eligible or board-certified in Cardiology. Additional training in MR and/or CT imaging is desirable but not essential. The candidate will participate in teaching in addition to full-time clinical activities. An M.D., D.O., or equivalent is required.

The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at Cultural North Star.

All aspects of searches are confidential and all candidates are expected to review and abide by UC Regents Policy 1111 on Statement on Ethical Values and Standards of Conduct.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

To apply, please click here – JPF11010

Posted July 21, 2026

The Division of Cardiology in the Department of Medicine at the David Geffen School of Medicine at UCLA is seeking applications for Clinician-Educator positions in the Health Sciences Clinical Professor series at the Instructor, Assistant, Associate, or full Professor ranks. Candidates with non-invasive training and interventional training are being recruited. These positions involve participating in university-based cardiology practices throughout the Central Coast (Santa Maria, San Luis Obispo, and Paso Robles). Candidates are expected to be board-eligible or board-certified in Cardiology. Additional training in MR and/or CT imaging is desirable but not essential. The candidate will participate in teaching in addition to full-time clinical activities. An M.D., D.O., or equivalent is required.

The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at Cultural North Star.

All aspects of searches are confidential and all candidates are expected to review and abide by UC Regents Policy 1111 on Statement on Ethical Values and Standards of Conduct.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

To apply, please click here – JPF11009

Posted July 21, 2026

The Division of Cardiology in the Department of Medicine at the David Geffen School of Medicine at UCLA is seeking applications for Clinician-Educator positions in the Health Sciences Clinical Professor series at the Instructor, Assistant, Associate, or full Professor ranks. The position involves participating in university-based general cardiology practices throughout the greater Los Angeles area. Candidates are expected to be board-eligible or board-certified in Cardiology. Additional training in EP, MR and/or CT imaging is desirable but not essential. The candidate will participate in teaching medical students, residents and cardiology fellows, in addition to full-time clinical activities. An M.D., D.O., or equivalent is required.

The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at Cultural North Star.

All aspects of searches are confidential and all candidates are expected to review and abide by UC Regents Policy 1111 on Statement on Ethical Values and Standards of Conduct.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

To apply, please click here – JPF11008