Placenta Accreta

Welcome to UCLA Health's Advanced Maternal Hemorrhage and Accreta Care Program

If you or a loved one is facing a high-risk pregnancy due to abnormal placental conditions or concerns about severe bleeding, you are not alone. At UCLA Health's Advanced Maternal Hemorrhage and Accreta Care Program, our compassionate team brings together leading experts from multiple specialties to provide the safest, most advanced care for mothers and babies with complex needs. We are here to support you every step of the way, offering clear information, personalized treatment options, and the latest evidence-based therapies so you can feel confident and cared for during this important time.

Key Elements of Our Care

1. Multidisciplinary Expertise: Our team includes specialists in maternal-fetal medicine, surgery, anesthesia, neonatology, nursing, social work, and many others. We work together to create a personalized care plan just for you.
2. Individualized Support and Advanced Treatment Options: From your first appointment through delivery and recovery, you’ll have a dedicated care coordination and access to counseling, education, and support services. We use the latest medical and surgical techniques and devices including aortic balloon occlusion to ensure the best possible outcomes for both you and your baby.
3. Clear communication and family-center care: We make sure you understand every step of your care. Our team is always ready to answer your questions and address your concerns. We include your family in the care process, respecting your wishes and making sure you feel supported throughout your journey.
4. Advancing Knowledge Through Research: As surgeon-scientists, our accreta team actively involved in cutting-edge research. Our team at UCLA collaborates across disciplines to address the most pressing questions with a focus on improving care for patients with placenta accreta spectrum and related conditions.

Current Studies

The Afshar Lab

UCLA Perinatal Biospecimen Repository

Patient Resources

National Accreta Foundation

Placenta Accreta for Patients

Publications

• Biology and Pathophysiology of Placenta Accreta Spectrum Disorder
  Afshar Y, Kashani Ligumsky L, Bartels HC, Krakow D. Obstet Gynecol. 2025 Jun 1.
  https://pubmed.ncbi.nlm.nih.gov/40209229
• Placenta accreta spectrum
  Jauniaux E, Aplin JD, Fox KA, Afshar Y, Hussein AM, Jones CJP, Burton GJ. Nat Rev Dis Primers. 2025 Jun 5.
  https://pubmed.ncbi.nlm.nih.gov/40473652
• Placenta Accreta Spectrum, Present and Future: The Eunice Kennedy Shriver National Institute of Child Health and Human Development Workshop Summary
  Duzyj CM, Einerson BD, Afshar Y, Fox KA, Saad AF, Carusi DA, Herrera CL, Lyell DJ, Abuhamad AZ, Farber MK, Roberts AC, Hobson SR, Sentilhes L, Sibai BM, Matsuo K, Terlizzi K, Shainker SA, Silver RM, Bartels HC, Shipp TD, Huang M, Cahill AG, Wright JD, Saade GR, Longo M. Obstet Gynecol. 2025 Jun 1.
  https://pubmed.ncbi.nlm.nih.gov/40311146
• Outcomes in REBOA by Sex: Results From the American Association of Surgery for Trauma (AAST) Aortic Occlusion and Resuscitation for Trauma and Acute Care Surgery (AORTA) Trial
  Shaw JF, Kawai K, Chervu NL, Brenner ML. Am Surg. 2025 Oct.
  https://pubmed.ncbi.nlm.nih.gov/40538026
• Updates and Knowledge Gaps in Placenta Accreta Spectrum Biology
  Kashani-Ligumsky L, Scott O, Martinez G, Jeong A, Yin O, Shah S, Wang A, Zhu Y, Afshar Y. Clin Obstet Gynecol. 2025 Jun 1.
  https://pubmed.ncbi.nlm.nih.gov/40257851
• Impact of Labor in Primary Cesarean Delivery on Subsequent Risk of Placenta Accreta
  Kashani Ligumsky L, Lopian M, Jeong A, Desmond A, Elmalech A, Many A, Martinez G, Krakow D, Afshar Y. Am J Perinatol. 2025 Sep 16.
  https://pubmed.ncbi.nlm.nih.gov/40957594
• Placenta accreta spectrum disorder at single-cell resolution: a loss of boundary limits in the decidua and endothelium
  Afshar Y, Yin O, Jeong A, Martinez G, Kim J, Ma F, Jang C, Tabatabaei S, You S, Tseng HR, Zhu Y, Krakow D. Am J Obstet Gynecol. 2024 Apr.
  https://pubmed.ncbi.nlm.nih.gov/38296740
• Maternal hemodynamics during aortic occlusion with REBOA in patients with placenta accreta spectrum disorder
  Nieto-Calvache AJ, López-Girón MC, Burgos-Luna JM, Messa-Bryon A, Monroy A, López LJ, Rodríguez F, Caicedo Y, Brenner M, Ordoñez CA. J Matern Fetal Neonatal Med. 2022 Dec.
  https://pubmed.ncbi.nlm.nih.gov/33618605
• Resuscitative Endovascular Balloon Occlusion of the Aorta: What You Need to Know
  Shaw J, Brenner M. J Trauma Acute Care Surg. 2025 Jun 1.
  https://pubmed.ncbi.nlm.nih.gov/39969564
• General Management Considerations for Placenta Accreta Spectrum
  Einerson BD, Sandlin AT, Afshar Y, Sharawi N, Fox KA, Newton JM, Shainker SA, Pezeshkmehr A, Carusi DA, Moroz L. Am J Perinatol. 2023 Jul.
  https://pubmed.ncbi.nlm.nih.gov/37336221