The Science of the Aging Brain
A NeuroNote collection that lets you explore UCLA-curated research in a new way. Ask big questions at any level of understanding.
Mechanisms of Brain Decline
Clues on dementia from genes, immunity and sex
I study why dementia looks different from person to person by tracing how genes, the brain’s immune system and biological sex work together to drive decline. By mapping how these factors interact in brain tissue, I aim to reveal who is at risk, why two people with the same diagnosis progress differently, and which treatments are most likely to help.
Use this collection to ask questions at any level, follow answers back to the sources, and see how a more personal understanding of cognitive decline can point to better prevention.
Dr. Jessica Rexach
A Place for Infinite Curiosity
Here’s how it works:
- Sources are curated by UCLA Health and Dr. Jessica Rexach.
- Ask a question and the collection provides answers only from these sources.
- Open any paper, talk or explainer to go deeper.
Try Asking Questions Like:
In plain language, what is a biomarker?
What do genes have to do with dementia risk?
Explain to me like I’m ten-years-old: What is APOE?
Simply, how do hormones influence dementia risks?
Why does this research matter?
