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Neurophysiologic mechanisms of freezing of gait: disentangling phenotypic heterogeneity with mobile EEG and wearable kinematic sensors
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Brief Summary
This is a Basic science study investigating electrophysiological mechanisms of freezing of gait. Study involves EEG and accelerometer recordings during walking in a clinic setting. Patients are asked not to take morning medications on day of study. Study duration: 2-3 hours in one visit to UCLA.
Eligibility
Minimum Age
Maximum Age
Key inclusions: Diagnosis of idiopathic Parkinsons disease by movement disorders neurologist. Also recruiting age-matched healthy controls
Key Exclusions:
- Dementia (defined as MOCA < 19)
- Active hallucinations or psychosis
- Contraindications to MRI (metal implant, claustrophobia).
- History of Deep Brain Surgery (DBS)
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Study Stats
Protocol No.
21-000624
Category
Brain/Neurological Diseases
Healthy Volunteers
Principal Investigator
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