Open Actively Recruiting

Effect of Patient Preference for Intraoperative Opioid Use on Early Postoperative Quality of Recovery

About

Brief Summary

Substituting the administration of opioids with a combination of alternative analgesics, known as opioid-free anesthesia (OFA), is gaining in popularity today and is typically administered as part of a larger multimodal strategy. However, OFA adoption is not as common today as one could expect from the potential benefits of limiting opioid use and patient involvement in the decision may impact its adoption. Relevant shared decision-making process with patients concerning the use or limited use of opioids could improve patient autonomy and empowerment. There have been no studies that have evaluated patient preference regarding opioid use and its potential impact on the quality of recovery.

The aim of this study is to compare the effect of patient preference on intraoperative opioid use on early postoperative quality of recovery following moderate risk laparoscopic/robotic abdominal surgery.

Primary Purpose
Treatment
Study Type
Interventional
Phase
N/A

Eligibility

Gender
All
Healthy Volunteers
No
Minimum Age
18 Years
Maximum Age
N/A

Inclusion Criteria:

  • Age >18 years.
  • Undergoing elective intermediate risk surgery under general anesthesia (robotic or laparoscopic assisted urological, gynecological or abdominal surgery).
  • American Society Anesthesiologists physical status classification system grades of I-IV.
  • English speaking.
  • Informed consent signed.

Exclusion Criteria:

  • Diagnosis of chronic pain
  • Preoperative prescribed opioids
  • Pregnancy or lactation.
  • History of mental disorders.
  • Contraindications to study drug (lidocaine, magnesium, dexmedetomidine, ketamine)
  • Patient is participating in another interventional trial
  • Patient is under judicial protection or is an adult under guardianship.

Join this Trial

Contact our clinical trial navigators for opportunities that may be suitable for you
Share:
Study Stats
Protocol No.
24-5789
Category
Healthy Volunteers
Contact
Jennifer Scovotti
Location
  • UCLA Santa Monica
  • UCLA Westwood
For Providers
NCT No.
NCT06855641
For detailed technical eligibility, visit ClinicalTrials.gov.