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Water-Soluble Contrast Induced Intestinal Stimulation for the Treatment of Small Bowel Obstruction: A Feasibility Study

About

Brief Summary

Small bowel obstruction (SBO) is common yet, how to best manage it remains unknown. One approach is to administer water soluble oral contrast (WSC) and the obtain x-rays to determine how well the bowel is functioning. WSC may help resolve SBO by stimulating the bowel by itself. The intent of this study is to determine if the x-ray component of this therapeutic approach is necessary.

Primary Purpose

Treatment

Study Type

Interventional

Phase

N/A

Eligibility

Gender

All

Healthy Volunteers

Minimum Age

18 Years

Maximum Age

80 Years

Inclusion Criteria:

Documentation of aSBO as evidenced by one or more clinical features meeting the following criteria:
- Nausea
- Emesis
- Abdominal pain
- Distended abdomen
- CT evidence of aSBO
- Known abdominal surgical history.
Written informed consent obtained from subject.

Exclusion Criteria:

Unable to provide consent for the study.
Pregnant or breastfeeding.
Presence of a condition or abnormality that in the opinion of the investigator would compromise the safety of the patient or the quality of the data.
Unstable angina or recent myocardial infarction or stroke within 6 months
Patients with peritonitis or who require immediate surgery.
Non-adhesive SBO, including.
- Paralytic Ileus
- Incarcerated hernia
- Fecal impaction
- Intra-abdominal malignancy
- Early aSBO within 4 weeks of a prior abdominal operation