Open Actively Recruiting

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

About

Brief Summary

A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have cancer cachexia.

Primary Purpose
Treatment
Study Type
Interventional
Phase
Phase 2

Eligibility

Gender
All
Healthy Volunteers
No
Minimum Age
18 Years
Maximum Age
N/A

Inclusion Criteria:

  • Documented active diagnosis of colorectal cancer.
  • Cachexia defined by Fearon criteria of weight loss.
  • Signed informed consent.

Exclusion Criteria:

  • Current active reversible causes of decreased food intake.
  • Receiving tube feedings or parenteral nutrition at the time of Screening or Randomization.
  • Have cachexia caused by other reasons.
Study Stats
Protocol No.
25-1325
Category
Colorectal Cancer
Contact
JENNA DAVIS
Location
  • UCLA Burbank
  • UCLA Porter Ranch
  • UCLA Santa Monica
  • UCLA Westlake Village
For Providers
NCT No.
NCT07033026
For detailed technical eligibility, visit ClinicalTrials.gov.