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An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

About

Brief Summary

A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have cancer cachexia.

Primary Purpose
The main objective of the intervention(s) being evaluated by the clinical trial. Learn more
Treatment
Study Type
The nature of the investigation or investigational use for which clinical study information is being submitted. Learn more
Interventional
Phase
Phase 2

Eligibility

Gender
All
Healthy Volunteers
No
Minimum Age
18 Years
Maximum Age
N/A

Inclusion Criteria:

  • Documented active diagnosis of colorectal cancer.
  • Cachexia defined by Fearon criteria of weight loss.
  • Signed informed consent.

Exclusion Criteria:

  • Current active reversible causes of decreased food intake.
  • Receiving tube feedings or parenteral nutrition at the time of Screening or Randomization.
  • Have cachexia caused by other reasons.
Study Stats
Protocol No.
25-1325
Category
Colorectal Cancer
Contact
  • Jenna Davis
Location
  • UCLA Burbank
  • UCLA Porter Ranch
  • UCLA Santa Monica
  • UCLA Westlake Village
For Providers
NCT No.
NCT07033026
For detailed technical eligibility, visit ClinicalTrials.gov.