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Illustration of T cells attacking cancer cells with a DNA model.
Cancer,
Science & Research

DNA copy-number changes help melanoma develop resistance to immunotherapy, UCLA study finds

A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential strategy to prevent or reverse that resistance.
October 31, 2025   |  
4 min read
group of women
Cancer,
Science & Research

Adding chemotherapy to radiation causes greater short-term decline in quality of life for patients with cervical cancer

A new study co-led by investigators at UCLA Health found that women with early-stage cervical cancer who received radiation plus chemotherapy reported a greater short-term decline in quality of life compared to those who received radiation alone.
October 22, 2025   |  
3 min read
Microscopy image showing blood stem cell-engineered CAR-NKT cells (blue) attacking a human solid tumor cell (magenta)
Cancer,
Science & Research

UCLA scientists develop one-product-fits-all immunotherapy for breast cancer

UCLA researchers have developed a CAR-NKT cell therapy that has shown to be more effective than current immunotherapies at fighting cancer in tumor samples from late-stage triple-negative breast cancer patients.
October 21, 2025   |  
4 min read
Dr. Antoni Ribas in the lab.
Cancer,
Science & Research

Dr. Antoni Ribas recognized for transforming cancer treatment

Dr. Ribas was named the 17th Annual Weinman Award recipient in recognition of his pioneering research that led to the development of novel and effective therapies for patients with metastatic melanoma, a disease once considered untreatable.
October 21, 2025   |  
2 min read
Guam Regional Medical Center team members pose for a photo.
Cancer,
Healthy Lifestyle
Microscopic image of colon cancer cells
Cancer,
Science & Research

Combination of immunotherapy and targeted therapy improves survival for patients with advanced colorectal cancer

A new study led by UCLA found that combining zanzalintinib and atezolizumab helped patients with metastatic colorectal cancer live longer and control their disease better than with the standard treatment drug regorafenib.
October 20, 2025   |  
4 min read
epigenetics
Cancer,
Science & Research

ESMO: 10-year survival data for lung cancer immunotherapy, new PSMA-targeted therapy for recurrent prostate cancer, promising results in metastatic colorectal and urothelial cancers

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center will present new research at the ESMO Congress, covering advances in immunotherapy, targeted therapies, and new combination therapies for aggressive and hard-to-treat cancers.
October 19, 2025   |  
3 min read
Headshot of Jingran Ji
Cancer,
Science & Research

Dr. Jingran Ji receives NIH GEMSSTAR award to advance research in cancer and aging

The award will support Ji’s research into how cancer treatments affect physical function and quality of life in older adults with gastroesophageal cancer.
October 16, 2025   |  
2 min read
Rich Everson, Sophie and Robert Chong
Cancer,
Science & Research

Novel procedure helps treat New Zealand teen with brain cancer

Sophie Clibborn underwent stereotactic laser ablation, a minimally invasive procedure that uses MRI guidance to precisely target the tumor and destroy it with focused laser energy.
October 13, 2025   |  
5 min read
A bone cancer cell.
Cancer,
Science & Research

Scientists create radiotheranostic approach designed to combat aggressive cancers

UCLA scientists, together with a team of international collaborators, have identified a promising new treatment strategy that can detect, kill and reprogram aggressive, treatment-resistant tumors like osteosarcomas and glioblastoma.
October 8, 2025   |  
5 min read
Two doctors in a lab
Cancer,
Science & Research

For rapid, precise lung cancer resections, researchers look to a pen

Dr. Bryan Burt of UCLA Health is leading research on new technology for real-time evaluation of surgical tissue.
October 6, 2025   |  
4 min read
radiation therapy
Cancer,
Science & Research

Short-course radiation therapy after prostate surgery helps keep cancer from returning

Investigators found that SBRT, a form of high-dose radiation delivered in just five sessions, after prostate surgery is safe and as effective as traditional, longer courses of radiation in preventing prostate cancer from returning.
October 2, 2025   |  
3 min read
Tiki Hayes headshot
Cancer,
Science & Research

Dr. Tiki Hayes awarded grant to help unlock treatments for EGFR-mutant lung cancer

The new funding will support Hayes in developing new lab models using human lung cells and 3D organoids to better understand how these rare EGFR mutations drive cancer growth.
October 1, 2025   |  
2 min read
photo collage of scientist kathrin plath on the left and scientist hanna mikkola on the right, both are in a lab setting
Cancer,
Science & Research

UCLA scientists receive $4.7 million in CIRM grants to advance novel stem cell-based treatments for female-specific diseases and leukemia in Down syndrome

UCLA scientists have received $4.7 million in grants from the California Institute for Regenerative Medicine, the state’s stem cell agency, to advance stem cell-based treatments for female-specific diseases and childhood leukemia in Down syndrome.
September 29, 2025   |  
3 min read
Amar Kishan, MD
Cancer,
Science & Research

Dr. Amar Kishan honored with Steven A. Leibel Memorial Award

Presented by the American Society for Radiation Oncology (ASTRO) and the American Board of Radiology (ABR) Foundation, the award recognizes outstanding principal investigators within the first decade of their careers following board certification.
September 29, 2025   |  
2 min read
figure of PSMA PET scans
Cancer,
Science & Research

ASTRO: New therapy delays progression of recurrent prostate cancer

Patients with recurring prostate cancer who were treated with a new PSMA-targeted radioligand therapy before stereotactic body radiotherapy went more than twice as long without their disease worsening compared with those who received SBRT alone.
September 28, 2025   |  
5 min read
radiation therapy
Cancer,
Science & Research

ASTRO: Targeted radioactive therapy for recurrent prostate cancer, new SBRT approaches, 5DCT-guided imaging advances and more

Physicians and scientists from the UCLA Health Jonsson Comprehensive Cancer Center will share the latest research and clinical trial results at the 2025 American Society for Radiation Oncology (ASTRO) Annual Meeting.
September 26, 2025   |  
6 min read