Marla D. Lipsyc-Sharf, MD

Marla Lipsyc-Sharf, MD

Clinical Instructor, Department of Medicine, Division of Hematology/Oncology

Languages

English

Education

Fellowship

Medical Oncology, Dana-Farber Cancer Institute/Mass General Brigham, Boston, MA, 2023

Degrees

MD, Columbia University, New York, NY, 2017
BS, Columbia University, New York, NY, 2013

Residency

Internal Medicine, Brigham and Women's Hospital, Boston, MA, 2020

Board Certification

Program in Clinical Effectiveness, Harvard T.H. Chan School of Public Health, Boston, MA, 2022

Contact Information

Scientific Interests

Dr. Lipsyc-Sharf's clinical-translational research is focused on circulating biomarkers, in particular circulating tumor DNA (ctDNA), for monitoring of patients' breast cancers and their treatment. Clinically, she focuses on the treatment and study of hormone receptor positive breast cancers and breast cancers in young women.

Highlighted Publications

Lipsyc-Sharf M, De Bruin EC, Santos K, et al. Circulating tumor DNA (ctDNA) and late recurrence in high-risk hormone receptor-positive, HER2- negative breast cancer. J Clin Oncol. 2022 Jun 4:JCO2200908. doi: 10.1200/JCO22.00908. Epub ahead of print. PMID: 35658506.

Goyette MA*, Lipsyc-Sharf M*, Polyak K. Clinical and translational relevance of intratumor heterogeneity. Trends Cancer. 2023 May 27:S2405-8033(23)00084-5. doi: 10.1016/j.trecan.2023.05.001. Epub ahead of print. PMID: 37248149. *Equal Contribution

Lipsyc-Sharf M, Tolaney SM. Elacestrant: who are optimal candidates for the first oral SERD? Ann Oncol. 2023 May;34(5):449-451. doi: 10.1016/j.annonc.2023.02.006. Epub 2023 Feb 20. PMID: 36813113.

Lipsyc-Sharf M, Jain E, Collins LC, et al. Genomics of ERBB2-Positive Breast Cancer in Young Women Before and After Exposure to Chemotherapy Plus Trastuzumab. JCO Precis Oncol. 2023 Jun;7:e2300076. doi: 10.1200/PO.23.00076. PMID: 37364233.

Lipsyc-Sharf M, Partridge AH. Fertility and Sexual Health in Young Women with Early-Stage Breast Cancer. Surgical Oncology Clinics of North America, 2023, ISSN 1055-3207, https://doi.org/10.1016/j.soc.2023.05.012.