Xin Huang, PhD

The research interests in Dr. Xin Huang's lab include:
Epigenomics in Cancer, B-cell Development and Lymphomas, R-loops and DNA Damage/Repair, and RNA Binding Proteins in Gene Epigenetic Regulation. 

Zhang X, Zhang X, Huang X, Iqbal J, et al. and Fu K. (2024) MiR-17∼92 is involved in NF-κB activation via targeting the ubiquitin-editing proteins to mediate RIP1 complex polyubiquit nations in ABC-DLBCL. Clinical Immunology doi: 10.1016/j.clim.2024.110297.

Huang X#, Balmer S, Lyu C, Xiang Y, et al. and Wang J#. (2024) ZFP281 controls transcri tional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1. Developmental Cell 59(4), 465-481. (#co-corresponding).

Nobre AR, Dalla E, Yang J, Huang X, Wullkopf L, et al. and Wang J, Aguirre-Ghiso JA. (2022) ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung. Nature Cancer 3(10): 1165-80.

Iqbal J*, Shen Y*, Huang X*, Liu Y, Wake L, et al. and Fu K, Chan WC. (2015) Global m croRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B cell lymphoma. Blood 125:1137-45 (*co-first).

Huang X, Meng B, Iqbal J, et al. and Chan WC, Fu K. (2013) Activation of STAT3 signaling pathway is associated with the poor survival in diffuse large B-cell lymphoma patients treated with R-CHOP. Journal of Clinical Oncology 31:4520-28.