UCLA cancer researcher William Speier, PhD

William Speier, PhD

Assistant Professor, Department of Radiological Sciences

Languages

English

Education

Fellowship

Neurosurgery, University of California, Los Angeles, CA, 2016

Degrees

PhD, University of California, Los Angeles, CA, 2015
MS, Johns Hopkins University, Baltimore, MD, 2008
BSc, Johns Hopkins University, Baltimore, MD, 2005

Contact Information

Scientific Interests

Dr. Speier's research focuses on the application of artificial intelligence to utilize biomedical data to improve clinical outcomes. His lab develops multi-modal models that combine biomarkers from a variety of sources, including radiology, pathology, molecular testing, and biosignal recordings, that can be used in the detection and prognosis of cancer. Dr. Speier works with clinical partners to translate these models from the bench to the bedside in order to improve patient care.

Highlighted Publications

Redekop, Sarma, Kinnaird, Sisk, Raman, Marks, Speier, Arnold. Attention-Guided Prostate Lesion Localization and Grade Group Classification with Multiple Instance Learning. MIDL 2022:975-987.

Li, Li, Polson, Wang, Speier, Arnold. High resolution histopathology image generation and segmentation through adversarial training. Medical Image Analysis 2022;75:102251.

Bulten, Kartasalo, Chen, Strom, Pinckaers, Ngpal, Cai, Steiner, Boven, Vink, Hulsbergen-van de Kaa, der Laak, Amin, Evans, van der Kwast, Allan, Humphrey, Gronberg, Samaratunga, Delahunt, Tsuzuki, Hakkinen, Egevad, Demkin, the PANDA challenge consortium. Artificial intelligence for diagnosis and Gleson grading of prostate cancer: the PANDA challenge. Nature Medicine 2022;28:154-163.

Zhuang, Ivezic, Feng, Shen, Radhachandran, Sant, Patel, Masamed, Arnold, Speier. Patient level thyroid cancer classification using attention multiple instance learning on fused multi scale ultrasound image features. AMIA 2023;1344.

Sant, Radhachandran, Ivezic, Lee, Livhits, Wu, Arnold, Yeh, Speier. From Bench-to-Bedside: How Artificial Intelligence is Changing Thyroid Nodule Diagnostics. Journal of Clinical Endocrinology & Metabolism 2024;109(7):1684-1693.