Mina S. Sedrak, MD, MS
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Scientific Interests
Dr. Sedrak is an internationally recognized physician-scientist and breast medical oncologist focused on improving the health and well-being of cancer patients and survivors. As Director of the Cancer and Aging Program, he leads interdisciplinary research at the intersection of cancer and aging. His research aims to understand how cancer treatments accelerate biological aging and to develop biology-driven precision strategies that prevent or mitigate accelerated aging after treatment.
Highlighted Publications
Ji J, Sun CL, Cohen HJ, Synold T, Muss H, Sedrak MS. Inflammation and Clinical Decline After Adjuvant Chemotherapy in Older Adults with Breast Cancer: Results From the Hurria Older Patients Prospective Study. J Clin Oncol. 2022 Sep 20:JCO2201217. PMID: 36126235.
Sedrak MS*, Magnuson A*, Gross CP, Tew WP, Klepin HD, Wildes TM, Muss HB, Dotan E, Freedman RA, O'Connor T, Dale W, Cohen HJ, Katheria V, Arsenyan A, Levi A, Kim H, Mohile S, Hurria A, Sun CL. Development and Validation of a Risk Tool for Predicting Severe Toxicity in Older Adults Receiving Chemotherapy for Early-Stage Breast Cancer. J Clin Oncol. 2021 Feb 20;39(6):608-618 PMID: 33444080; PMCID: PMC8189621. (*=co-first authors)
Sedrak MS, Freedman RA, Cohen HJ, Muss HB, Jatoi A, Klepin HD, Wildes TM, Le- Rademacher JG, Kimmick GG, Tew WP, George K, Padam S, Liu J, Wong AR, Lynch A, Djulbegovic B, Mohile SG, Dale W. Older adult participation in cancer clinical trials: A systematic review of barriers and interventions. CA Cancer J Clin. 2021 Jan;71(1):78-92. PMID: 33002206; PMCID: PMC7854940.
Sedrak MS, Mohile SG, Sun V, Sun CL, Chen BT, Li D, Wong AR, George K, Padam S, Liu J, Katheria V, Dale W. Barriers to clinical trial enrollment of older adults with cancer: A qualitative study of the perceptions of community and academic oncologists. J Geriatr Oncol. 2020 Mar;11(2):327 334. PMID: 31375399; PMCID: PMC6989372.
Sedrak MS, Myers JS, Small DS, Nachamkin I, Ziemba JB, Murray D, Kurtzman GW, Zhu J, Wang W, Mincarelli D, Danoski D, Wells BP, Berns JS, Brennan PJ, Hanson CW, Dine CJ, Patel MS. Effect of a Price Transparency Intervention in the Electronic Health Record on Clinician Ordering of Inpatient Laboratory Tests: The PRICE Randomized Clinical Trial. JAMA Intern Med. 2017 Jul 1;177(7):939-945. PMID: 28430829; PMCID: PMC5543323.