Alexander Strudwick Young , BSc, MPhil, DPhil

Genetic epidemiology of cancer 

Polygenic risk scores for cancer and their use in screening

Application of IVF technologies to reduce inherited cancer risk

An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference. Alemu R, Terskaya A, Howell M, Guan J, Sands H, Kleinman A; 23andMe Research Team; Bann D, Morris T, Ploubidis GB, Fitzsimons E, Harris KM, Caspi A, Corcoran DL, Moffitt TE, Poulton R, Sugden K, Williams BS, Steptoe A, Ajnakina O, Vainik U, Esko T; Estonian Biobank Research Team; Campbell A, Hayward C, Iacono WG, McGue M, Krueger RF, Docherty AR, Shabalin AA, Hertwig R, Koellinger P, Richter D, Goebel J, Ahlskog R, Oskarsson S, Magnusson PKE, Harden KP, Tucker-Drob EM, Pahnke CKL, Maj C, Spinath FM, Herd P, Freese J, Laibson D, Meyer MN, Jala J, Cesarini D, Young AS, Turley P, Benjamin DJ, Okbay A. bioRxiv [Preprint]. 2025 Aug 14:2025.05.14.653986. doi: 10.1101/2025.05.14.653986. PMID: 40463245; PMCID: PMC12132466.

Development and validation of polygenic scores for within-family prediction of disease risks. Spencer Moore, Ivan Davidson, Jonathan Anomaly, Jeremiah H. Li, Mohammad Ahangari, Lauren Moissiy, Michael Christensen, Alexander Strudwick Young, David Stern, Tobias Wolfram, medRxiv 2025.08.06.25333145; doi: https://doi.org/10.1101/2025.08.06.25333145

ImputePGTA: accurate embryo genotyping and polygenic scoring from ultra-lowpass sequencing. Jeremiah H. Li, Tobias Wolfram, Ivan Davidson, Justin Schleede, Jennifer Swift, Spencer Moore, David Stern, Michael Christensen, Alexander Strudwick Young. medRxiv 2025.11.07.25339763; doi: https://doi.org/10.1101/2025.11.07.25339763