Alexander Hoffmann, PhD

The research of Dr. Alex Hoffmann's laboratory focuses on the signaling systems that ensure that cells respond to noxious stimuli and pathogens appropriately, and how they change during cell differentiation and carcinogenesis.

Mulero MC, Ferres-Marco D, Islam A, Margalef P, Pecoraro M, Toll A, Drechsel N, Charneco C, Davis S, Bellora N, Gallardo F, Lopez-Arribillaga E, Asensio-Juan E, Rodilla V, Gonzalez J, Iglesias M, Shih V, Mar Alba M, Di Croce L, Hoffmann A, Miyamoto S, Villa-Freixa J, Lopez-Bigas N, Keyes WM, Dominguez M, Bigas A, Espinosa L. Chromatin-bound IkappaBalpha regulates a subset of polycomb target genes in differentiation and cancer. Cancer Cell. 2013 Aug 12;24(2):151-66. doi: 10.1016/j.ccr.2013.06.003. Epub 2013 Jul 11.